ENSG00000128283


Homo sapiens

Features
Gene ID: ENSG00000128283
  
Biological name :CDC42EP1
  
Synonyms : CDC42 effector protein 1 / CDC42EP1 / Q00587
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.1
Gene start: 37560447
Gene end: 37569405
  
Corresponding Affymetrix probe sets: 204693_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000249014
Ensembl peptide - ENSP00000411682
Ensembl peptide - ENSP00000405006
Ensembl peptide - ENSP00000403710
NCBI entrez gene - 11135     See in Manteia.
OMIM - 606084
RefSeq - XM_006724107
RefSeq - XM_017028541
RefSeq - XM_006724109
RefSeq - NM_152243
RefSeq - XM_006724108
RefSeq Peptide - NP_689449
swissprot - Q00587
swissprot - B0QYC8
swissprot - B0QYC6
swissprot - B0QYC7
Ensembl - ENSG00000128283
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42ep1aENSDARG00000079549Danio rerio
 cdc42ep1bENSDARG00000077792Danio rerio
 CDC42EP1ENSGALG00000038556Gallus gallus
 Cdc42ep1ENSMUSG00000049521Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H3Q1 / CDC42EP4 / CDC42 effector protein 4ENSG0000017960424
Q6NZY7 / CDC42EP5 / CDC42 effector protein 5ENSG0000016761716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR029273  Cdc42 effector
 IPR036936  CRIB domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0030838 positive regulation of actin filament polymerization IBA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017049 GTP-Rho binding IBA
 molecular_functionGO:0098641 cadherin binding involved in cell-cell adhesion IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr