ENSG00000179604


Homo sapiens

Features
Gene ID: ENSG00000179604
  
Biological name :CDC42EP4
  
Synonyms : CDC42 effector protein 4 / CDC42EP4 / Q9H3Q1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.1
Gene start: 73283624
Gene end: 73312175
  
Corresponding Affymetrix probe sets: 214721_x_at (Human Genome U133 Plus 2.0 Array)   218062_x_at (Human Genome U133 Plus 2.0 Array)   218063_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463877
Ensembl peptide - ENSP00000485861
Ensembl peptide - ENSP00000464104
Ensembl peptide - ENSP00000338258
Ensembl peptide - ENSP00000404270
Ensembl peptide - ENSP00000462231
NCBI entrez gene - 23580     See in Manteia.
OMIM - 605468
RefSeq - NM_012121
RefSeq - XM_005257182
RefSeq Peptide - NP_036253
swissprot - Q9H3Q1
swissprot - J3QR93
swissprot - J3KRZ9
swissprot - J3QQS6
swissprot - B2R6D8
Ensembl - ENSG00000179604
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42ep4aENSDARG00000101457Danio rerio
 cdc42ep4bENSDARG00000045036Danio rerio
 CDC42EP4ENSGALG00000023364Gallus gallus
 Q9JM96ENSMUSG00000041598Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q00587 / CDC42EP1 / CDC42 effector protein 1ENSG0000012828326
Q6NZY7 / CDC42EP5 / CDC42 effector protein 5ENSG0000016761717


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR029273  Cdc42 effector


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IBA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017049 GTP-Rho binding NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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