ENSG00000122545


Homo sapiens

Features
Gene ID: ENSG00000122545
  
Biological name :SEPT7
  
Synonyms : Q16181 / SEPT7 / septin 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p14.2
Gene start: 35800932
Gene end: 35907105
  
Corresponding Affymetrix probe sets: 1565823_at (Human Genome U133 Plus 2.0 Array)   213151_s_at (Human Genome U133 Plus 2.0 Array)   217721_at (Human Genome U133 Plus 2.0 Array)   244508_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381992
Ensembl peptide - ENSP00000344868
Ensembl peptide - ENSP00000381993
Ensembl peptide - ENSP00000489596
Ensembl peptide - ENSP00000489538
Ensembl peptide - ENSP00000489480
Ensembl peptide - ENSP00000489466
Ensembl peptide - ENSP00000489192
Ensembl peptide - ENSP00000444240
Ensembl peptide - ENSP00000413507
NCBI entrez gene - 989     See in Manteia.
OMIM - 603151
RefSeq - XM_017012863
RefSeq - NM_001011553
RefSeq - NM_001242956
RefSeq - NM_001788
RefSeq - XM_006715806
RefSeq - XM_011515656
RefSeq - XM_011515661
RefSeq - XM_017012855
RefSeq - XM_017012856
RefSeq - XM_017012857
RefSeq - XM_017012858
RefSeq - XM_017012859
RefSeq - XM_017012860
RefSeq - XM_017012861
RefSeq - XM_017012862
RefSeq Peptide - NP_001011553
RefSeq Peptide - NP_001229885
RefSeq Peptide - NP_001779
swissprot - A0A0U1RRH9
swissprot - A0A0U1RRE1
swissprot - A0A0U1RRD1
swissprot - A0A0U1RQW0
swissprot - E7ES33
swissprot - Q16181
swissprot - Q5JXL7
swissprot - A0A024RA87
swissprot - G3V1Q4
swissprot - E7EPK1
swissprot - A0A0U1RRM2
Ensembl - ENSG00000122545
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sept7aENSDARG00000087647Danio rerio
 sept7bENSDARG00000052673Danio rerio
 SEPT7ENSGALG00000032830Gallus gallus
 Sept7ENSMUSG00000001833Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SEPT4 / O43236 / septin 4ENSG0000010838744
SEPT5 / Q99719 / septin 5ENSG0000018470243
AC000093.1ENSG0000028487442
SEPT2 / Q15019 / septin 2ENSG0000016838542
SEPT1 / septin 1ENSG0000018009641
SEPT9 / Q9UHD8 / septin 9ENSG0000018464034
SEPT3 / Q9UH03 / septin 3ENSG0000010016733
Q8IYM1 / SEPT12 / septin 12ENSG0000014062332


Protein motifs (from Interpro)
Interpro ID Name
 IPR008115  Septin 7
 IPR016491  Septin
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030379  Septin-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0016476 regulation of embryonic cell shape ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0051291 protein heterooligomerization IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060271 cilium assembly ISS
 biological_processGO:1902857 positive regulation of non-motile cilium assembly IMP
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0005930 axoneme IDA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0031105 septin complex IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097227 sperm annulus IDA
 cellular_componentGO:0097730 non-motile cilium IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005198 structural molecule activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069956 MAPK6 / Q16659 / mitogen-activated protein kinase 6  / reaction / complex
 ENSG00000167617 Q6NZY7 / CDC42EP5 / CDC42 effector protein 5  / reaction
 ENSG00000149798 O14613 / CDC42EP2 / CDC42 effector protein 2  / reaction
 ENSG00000163171 Q9UKI2 / CDC42EP3 / CDC42 effector protein 3  / reaction
 ENSG00000089022 Q8IW41 / MAPKAPK5 / mitogen-activated protein kinase-activated protein kinase 5  / complex / reaction






 

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