ENSG00000149798


Homo sapiens

Features
Gene ID: ENSG00000149798
  
Biological name :CDC42EP2
  
Synonyms : CDC42 effector protein 2 / CDC42EP2 / O14613
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.1
Gene start: 65314818
Gene end: 65322429
  
Corresponding Affymetrix probe sets: 209850_s_at (Human Genome U133 Plus 2.0 Array)   214014_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000279249
Ensembl peptide - ENSP00000431660
NCBI entrez gene - 10435     See in Manteia.
OMIM - 606132
RefSeq - XM_017017094
RefSeq - NM_006779
RefSeq Peptide - NP_006770
swissprot - O14613
Ensembl - ENSG00000149798
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42ep2ENSDARG00000053959Danio rerio
 Q8JZX9ENSMUSG00000045664Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UKI2 / CDC42EP3 / CDC42 effector protein 3ENSG0000016317146


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR017363  Cdc42 effector protein 2
 IPR029273  Cdc42 effector


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization NAS
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030036 actin cytoskeleton organization IDA
 biological_processGO:0030838 positive regulation of actin filament polymerization IDA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IDA
 biological_processGO:0031334 positive regulation of protein complex assembly TAS
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 molecular_functionGO:0001515 opioid peptide activity IEA
 molecular_functionGO:0005096 GTPase activator activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017049 GTP-Rho binding IPI


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069956 MAPK6 / Q16659 / mitogen-activated protein kinase 6  / reaction
 ENSG00000122545 SEPT7 / Q16181 / septin 7  / reaction
 ENSG00000089022 Q8IW41 / MAPKAPK5 / mitogen-activated protein kinase-activated protein kinase 5  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr