ENSDARG00000053959


Danio rerio

Features
Gene ID: ENSDARG00000053959
  
Biological name :cdc42ep2
  
Synonyms : CDC42 effector protein (Rho GTPase binding) 2 / cdc42ep2
  
Possible biological names infered from orthology : CDC42 effector protein 2 / O14613 / Q8JZX9
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 37720777
Gene end: 37730189
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000070562
Ensembl peptide - ENSDARP00000147431
NCBI entrez gene - 541404     See in Manteia.
RefSeq - NM_001013531
RefSeq Peptide - NP_001013549
swissprot - Q5BKX1
ZFIN ID - ZDB-GENE-050320-104
Ensembl - ENSDARG00000053959
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O14613ENSG00000149798Homo sapiens
 Q8JZX9ENSMUSG00000045664Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdc42ep3 / CDC42 effector protein (Rho GTPase binding) 3 / Q9UKI2* / CDC42 effector protein 3*ENSDARG0000005278340
zgc:154093ENSDARG0000005589731


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR029273  Cdc42 effector


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0030838 positive regulation of actin filament polymerization IBA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017049 GTP-Rho binding IBA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000032103 mapk6 / mitogen-activated protein kinase 6 / Q16659* / Q61532*  / reaction
 ENSDARG00000028082 mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*  / reaction






 

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contact: otassy@igbmc.fr