ENSMUSG00000045664


Mus musculus

Features
Gene ID: ENSMUSG00000045664
  
Biological name :Cdc42ep2
  
Synonyms : Cdc42 effector protein 2 / Cdc42ep2 / Q8JZX9
  
Possible biological names infered from orthology : O14613
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 5917556
Gene end: 5924816
  
Corresponding Affymetrix probe sets: 10465278 (MoGene1.0st)   1428750_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000059883
NCBI entrez gene - 104252     See in Manteia.
MGI - MGI:1929744
RefSeq - NM_026772
RefSeq Peptide - NP_081048
swissprot - Q8JZX9
Ensembl - ENSMUSG00000045664
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42ep2ENSDARG00000053959Danio rerio
 O14613ENSG00000149798Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CQC5 / Cdc42ep3 / Cdc42 effector protein 3 / Q9UKI2*ENSMUSG0000003653347


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR017363  Cdc42 effector protein 2
 IPR029273  Cdc42 effector


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0008360 regulation of cell shape ISO
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0045335 phagocytic vesicle IDA
 molecular_functionGO:0001515 opioid peptide activity IPI
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0017049 GTP-Rho binding IEA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029454 O54992 / Mapkapk5 / MAP kinase-activated protein kinase 5 / Q8IW41* / mitogen-activated protein kinase-activated protein kinase 5*  / reaction
 ENSMUSG00000042688 Mapk6 / Q61532 / Mitogen-activated protein kinase 6 / Q16659*  / reaction
 ENSMUSG00000001833 Sept7 / septin-7 isoform 2 / Q16181* / septin 7*  / reaction






 

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