ENSG00000163171


Homo sapiens

Features
Gene ID: ENSG00000163171
  
Biological name :CDC42EP3
  
Synonyms : CDC42 effector protein 3 / CDC42EP3 / Q9UKI2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p22.2
Gene start: 37641882
Gene end: 37738468
  
Corresponding Affymetrix probe sets: 209286_at (Human Genome U133 Plus 2.0 Array)   209287_s_at (Human Genome U133 Plus 2.0 Array)   209288_s_at (Human Genome U133 Plus 2.0 Array)   225685_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480549
Ensembl peptide - ENSP00000295324
Ensembl peptide - ENSP00000398062
Ensembl peptide - ENSP00000403298
Ensembl peptide - ENSP00000409147
NCBI entrez gene - 10602     See in Manteia.
OMIM - 606133
RefSeq - XM_011532482
RefSeq - NM_001270436
RefSeq - NM_001270437
RefSeq - NM_001270438
RefSeq - NM_006449
RefSeq Peptide - NP_001257365
RefSeq Peptide - NP_001257366
RefSeq Peptide - NP_001257367
RefSeq Peptide - NP_006440
swissprot - C9JKW5
swissprot - C9J7F7
swissprot - Q9UKI2
swissprot - C9JEZ4
Ensembl - ENSG00000163171
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42ep3ENSDARG00000052783Danio rerio
 CDC42EP3ENSGALG00000010551Gallus gallus
 Q9CQC5ENSMUSG00000036533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O14613 / CDC42EP2 / CDC42 effector protein 2ENSG0000014979838


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR029273  Cdc42 effector


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IBA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005519 cytoskeletal regulatory protein binding TAS
 molecular_functionGO:0017049 GTP-Rho binding IBA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069956 MAPK6 / Q16659 / mitogen-activated protein kinase 6  / reaction
 ENSG00000122545 SEPT7 / Q16181 / septin 7  / reaction
 ENSG00000089022 Q8IW41 / MAPKAPK5 / mitogen-activated protein kinase-activated protein kinase 5  / reaction






 

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