ENSDARG00000062748


Danio rerio

Features
Gene ID: ENSDARG00000062748
  
Biological name :pkn1b
  
Synonyms : pkn1b / protein kinase N1b
  
Possible biological names infered from orthology : P70268 / PKN1 / protein kinase N1 / Q16512 / Serine/threonine-protein kinase N1
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 5778954
Gene end: 5829501
  
Corresponding Affymetrix probe sets: Dr.16985.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000085450
swissprot - F1QXD6
ZFIN ID - ZDB-GENE-070424-87
Ensembl - ENSDARG00000062748
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PKN1ENSG00000123143Homo sapiens
 Pkn1ENSMUSG00000057672Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pkn1a / protein kinase N1a / PKN1* / Q16512* / P70268* / protein kinase N1* / Serine/threonine-protein kinase N1 *ENSDARG0000006018475
zgc:153916 / PKN2 (1 of many) / PKN2* / Q16513* / protein kinase N2*ENSDARG0000010129361
pkn2 / protein kinase N2 / Q16513*ENSDARG0000010198359
pkn3 / protein kinase N3 / Q6P5Z2* / Q8K045* / Serine/threonine-protein kinase N3 *ENSDARG0000007958552


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011072  HR1 rho-binding domain
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005622 intracellular IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017049 GTP-Rho binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases activate PKNs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr