ENSDARG00000068261


Danio rerio

Features
Gene ID: ENSDARG00000068261
  
Biological name :pros1
  
Synonyms : pros1 / protein S
  
Possible biological names infered from orthology : P07225 / protein S (alpha) / Q08761
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 343292
Gene end: 354166
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000089398
Ensembl peptide - ENSDARP00000117159
NCBI entrez gene - 768180     See in Manteia.
RefSeq - NM_001077323
RefSeq Peptide - NP_001070791
swissprot - F1QK29
swissprot - E9QII7
ZFIN ID - ZDB-GENE-061013-657
Ensembl - ENSDARG00000068261
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PROS1ENSGALG00000015409Gallus gallus
 PROS1ENSG00000184500Homo sapiens
 Pros1ENSMUSG00000022912Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gas6 / growth arrest-specific 6 / Q14393* / Q61592* / Growth arrest-specific protein 6 *ENSDARG0000000780437
shbg / sex hormone-binding globulin / P04278* / P97497*ENSDARG0000001949210


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000294  Gamma-carboxyglutamic acid-rich (GLA) domain
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017857  Coagulation factor-like, Gla domain superfamily
 IPR018097  EGF-like calcium-binding, conserved site
 IPR033189  Vitamin K-dependent protein S


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030195 negative regulation of blood coagulation IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Common Pathway of Fibrin Clot Formation
Gamma-carboxylation of protein precursors
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Removal of aminoterminal propeptides from gamma-carboxylated proteins
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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