ENSGALG00000015409


Gallus gallus

Features
Gene ID: ENSGALG00000015409
  
Biological name :PROS1
  
Synonyms : PROS1 / protein S
  
Possible biological names infered from orthology : P07225 / protein S (alpha) / Q08761
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 89665016
Gene end: 89695407
  
Corresponding Affymetrix probe sets: Gga.10157.2.S1_at (Chicken Array)   Gga.10157.2.S1_s_at (Chicken Array)   GgaAffx.20528.1.S1_at (Chicken Array)   GgaAffx.24672.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024809
NCBI entrez gene - 418430     See in Manteia.
RefSeq - XM_416641
swissprot - E1C6L4
Ensembl - ENSGALG00000015409
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pros1ENSDARG00000068261Danio rerio
 PROS1ENSG00000184500Homo sapiens
 Pros1ENSMUSG00000022912Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GAS6 / growth arrest specific 6 / Q14393* / Q61592* / Growth arrest-specific protein 6 *ENSGALG0000001682043


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000294  Gamma-carboxyglutamic acid-rich (GLA) domain
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017857  Coagulation factor-like, Gla domain superfamily
 IPR018097  EGF-like calcium-binding, conserved site
 IPR033189  Vitamin K-dependent protein S


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030195 negative regulation of blood coagulation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Common Pathway of Fibrin Clot Formation
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Removal of aminoterminal propeptides from gamma-carboxylated proteins
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008341 FURIN / furin, paired basic amino acid cleaving enzyme / P09958* / P23188*  / reaction
 ENSGALG00000001780 PROC / vitamin K-dependent protein C precursor / P33587* / P04070* / protein C, inactivator of coagulation factors Va and VIIIa* / Vitamin K-dependent protein C Vitamin K-dependent protein...  / reaction / complex






 

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