ENSDARG00000068280


Danio rerio

Features
Gene ID: ENSDARG00000068280
  
Biological name :GRB14
  
Synonyms : GRB14 / growth factor receptor bound protein 14
  
Possible biological names infered from orthology : Q14449 / Q9JLM9
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 50316921
Gene end: 50340720
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000089458
swissprot - E7F104
Ensembl - ENSDARG00000068280
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRB14ENSGALG00000020703Gallus gallus
 GRB14ENSG00000115290Homo sapiens
 Grb14ENSMUSG00000026888Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grb10b / growth factor receptor-bound protein 10b / GRB10* / Q60760* / Q13322* / growth factor receptor bound protein 10*ENSDARG0000003530861
grb10a / growth factor receptor-bound protein 10a / GRB10* / Q60760* / Q13322* / growth factor receptor bound protein 10*ENSDARG0000000201360
si:ch211-253b1.3 / GRB7* / Q03160* / Q14451* / growth factor receptor bound protein 7*ENSDARG0000004272652
raph1b / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b / RAPH1* / Q70E73* / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1*ENSDARG0000006173228
raph1a / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a / RAPH1* / Q70E73* / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1*ENSDARG0000000630127
apbb1ip / amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein / Q7Z5R6* / Q8R5A3* / amyloid beta precursor protein binding family B member 1 interacting protein*ENSDARG0000001650522


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015042  BPS (Between PH and SH2) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity IEA


Pathways (from Reactome)
Pathway description
Tie2 Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000028663 tek / TEK tyrosine kinase, endothelial / Q02763* / TEK receptor tyrosine kinase*  / complex / reaction






 

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