ENSDARG00000068820


Danio rerio

Features
Gene ID: ENSDARG00000068820
  
Biological name :h2afva
  
Synonyms : h2afva / H2A histone family, member Va / Q71PD7
  
Possible biological names infered from orthology : H2AFV / H2A histone family member V / Histone H2A.V / Q3THW5 / Q71UI9
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 13647288
Gene end: 13652687
  
Corresponding Affymetrix probe sets: Dr.12586.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000090434
Ensembl peptide - ENSDARP00000118054
NCBI entrez gene - 252913     See in Manteia.
RefSeq - NM_153644
RefSeq Peptide - NP_705930
swissprot - A2BFY9
swissprot - A2BFY8
swissprot - Q71PD7
ZFIN ID - ZDB-GENE-020717-1
Ensembl - ENSDARG00000068820
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 H2AFVENSG00000105968Homo sapiens
 H2afvENSMUSG00000041126Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
h2afvb / H2A histone family, member Vb / H2AFZ* / P0C0S5* / H2A histone family member Z*ENSDARG0000011649198


Protein motifs (from Interpro)
Interpro ID Name
 IPR002119  Histone H2A
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold
 IPR032454  Histone H2A, C-terminal domain
 IPR032458  Histone H2A conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006342 chromatin silencing IBA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0000790 nuclear chromatin IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
RNA Polymerase I Promoter Opening
RNA Polymerase I Chain Elongation
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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