ENSDARG00000068858


Danio rerio

Features
Gene ID: ENSDARG00000068858
  
Biological name :il2rga
  
Synonyms : il2rga / interleukin 2 receptor, gamma a
  
Possible biological names infered from orthology : AL590764.2 / Cytokine receptor common subunit gamma / Gm20489 / IL2RG / interleukin 2 receptor subunit gamma / P31785 / P34902
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 33544329
Gene end: 33557299
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000090505
NCBI entrez gene - 796604     See in Manteia.
RefSeq - NM_001128271
RefSeq Peptide - NP_001121743
swissprot - A8WH93
ZFIN ID - ZDB-GENE-080402-1
Ensembl - ENSDARG00000068858
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL2RGENSGALG00000005638Gallus gallus
 AL590764.2ENSG00000285171Homo sapiens
 IL2RGENSG00000147168Homo sapiens
 Gm20489ENSMUSG00000092463Mus musculus
 Il2rgENSMUSG00000031304Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
il2rgb / interleukin 2 receptor, gamma b / IL2RG* / P34902* / P31785* / Gm20489* / AL590764.2* / interleukin 2 receptor subunit gamma* / Cytokine receptor common subunit gamma *ENSDARG0000005370228


Protein motifs (from Interpro)
Interpro ID Name
 IPR003531  Short hematopoietin receptor, family 1, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0030098 lymphocyte differentiation IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-7 signaling
Interleukin-4 and Interleukin-13 signaling
Interleukin-15 signaling
Interleukin-9 signaling
Interleukin-2 signaling
Interleukin-21 signaling
Interleukin receptor SHC signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001078 thymus thymus decreased amount , abnormal
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 ZFA:0009046 T cell T cell absent , abnormal
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 ZFA:0009331 mature B cell mature B cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000076182 stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*  / complex
 ENSDARG00000010252 jak3 / Janus kinase 3 (a protein tyrosine kinase, leukocyte) / P52333* / Janus kinase 3*  / complex / reaction
 ENSDARG00000020625 jak1 / Janus kinase 1 / P23458*  / complex
 ENSDARG00000078649 il21r.2 / interleukin 21 receptor, tandem duplicate 2 / IL21R* / Q9JHX3* / Q9HBE5* / interleukin 21 receptor*  / complex
 ENSDARG00000028731 stat4 / signal transducer and activator of transcription 4 / Q14765*  / complex
 ENSDARG00000069961 il21r.1 / interleukin 21 receptor, tandem duplicate 1 / IL21R* / Q9JHX3* / Q9HBE5* / interleukin 21 receptor*  / complex
 ENSDARG00000075282 irs2b / insulin receptor substrate 2b / IRS2* / Irs3* / P81122* / Q9Y4H2* / insulin receptor substrate 2*  / complex
 ENSDARG00000054087 irs1 / insulin receptor substrate 1 / P35568*  / complex
 ENSDARG00000078970 il7r / interleukin 7 receptor / P16871* / P16872* / Interleukin-7 receptor subunit alpha *  / complex






 

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