ENSDARG00000068919


Danio rerio

Features
Gene ID: ENSDARG00000068919
  
Biological name :rad51c
  
Synonyms : rad51c / RAD51 paralog C
  
Possible biological names infered from orthology : DNA repair 3 / O43502 / Q924H5
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 32662886
Gene end: 32672508
  
Corresponding Affymetrix probe sets: Dr.14386.1.A1_at (Zebrafish Array)   NM_001006101_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000090614
Ensembl peptide - ENSDARP00000122101
NCBI entrez gene - 450081     See in Manteia.
RefSeq - NM_001006101
RefSeq Peptide - NP_001006101
swissprot - F1QQC9
ZFIN ID - ZDB-GENE-041010-204
Ensembl - ENSDARG00000068919
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAD51CENSGALG00000040380Gallus gallus
 O43502ENSG00000108384Homo sapiens
 Q924H5ENSMUSG00000007646Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rad51b / RAD51 paralog B / O15315* / O35719* / DNA repair 2 *ENSDARG0000003704625
xrcc3 / X-ray repair complementing defective repair in Chinese hamster cells 3 / O43542* / Q9CXE6* / X-ray repair cross complementing 3*ENSDARG0000001792824
rad51d / RAD51 paralog D / O75771*ENSDARG0000002640020


Protein motifs (from Interpro)
Interpro ID Name
 IPR013632  DNA recombination and repair protein Rad51-like, C-terminal
 IPR016467  DNA recombination and repair protein, RecA-like
 IPR020588  DNA recombination and repair protein RecA-like, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR033925  Rad51/DMC1/RadA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000707 meiotic DNA recombinase assembly IBA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0007131 reciprocal meiotic recombination IBA
 biological_processGO:0010212 response to ionizing radiation IBA
 biological_processGO:0042148 strand invasion IBA
 cellular_componentGO:0005657 replication fork IBA
 cellular_componentGO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex IBA
 molecular_functionGO:0000150 recombinase activity IBA
 molecular_functionGO:0000400 four-way junction DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IBA


Pathways (from Reactome)
Pathway description
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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