ENSDARG00000037046


Danio rerio

Features
Gene ID: ENSDARG00000037046
  
Biological name :rad51b
  
Synonyms : rad51b / RAD51 paralog B
  
Possible biological names infered from orthology : DNA repair 2 / O15315 / O35719
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 9474841
Gene end: 9568005
  
Corresponding Affymetrix probe sets: Dr.17199.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000053846
Ensembl peptide - ENSDARP00000119668
swissprot - F1QJ27
swissprot - F1R5P4
ZFIN ID - ZDB-GENE-040426-2750
Ensembl - ENSDARG00000037046
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAD51BENSGALG00000009491Gallus gallus
 O15315ENSG00000182185Homo sapiens
 O35719ENSMUSG00000059060Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rad51c / RAD51 paralog C / O43502* / Q924H5* / DNA repair 3 *ENSDARG0000006891924
rad51d / RAD51 paralog D / O75771*ENSDARG0000002640024
xrcc3 / X-ray repair complementing defective repair in Chinese hamster cells 3 / O43542* / Q9CXE6* / X-ray repair cross complementing 3*ENSDARG0000001792822


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR013632  DNA recombination and repair protein Rad51-like, C-terminal
 IPR016467  DNA recombination and repair protein, RecA-like
 IPR020588  DNA recombination and repair protein RecA-like, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030548  DNA repair protein RAD51 homologue 2
 IPR033925  Rad51/DMC1/RadA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000707 meiotic DNA recombinase assembly IBA
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0007131 reciprocal meiotic recombination IBA
 biological_processGO:0010212 response to ionizing radiation IBA
 biological_processGO:0042148 strand invasion IBA
 cellular_componentGO:0005657 replication fork IBA
 cellular_componentGO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex IBA
 molecular_functionGO:0000150 recombinase activity IBA
 molecular_functionGO:0000400 four-way junction DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IBA


Pathways (from Reactome)
Pathway description
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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