Manteia

ENSDARG00000068992

Danio rerio

Features

Gene ID:	ENSDARG00000068992

Biological name :	hspa8

Synonyms :	heat shock protein 8 / hspa8

Possible biological names infered from orthology :	Heat shock cognate 71 kDa protein / heat shock protein family A (Hsp70) member 8 / P11142 / P63017

Species:	Danio rerio

Chr. number:	10
Strand:	1
Band:
Gene start:	29849497
Gene end:	29858018

Corresponding Affymetrix probe sets:	Dr.24802.1.S1_a_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000141099 Ensembl peptide - ENSDARP00000150450 Ensembl peptide - ENSDARP00000090766 Ensembl peptide - ENSDARP00000119867 Ensembl peptide - ENSDARP00000121031 NCBI entrez gene - 573376 See in Manteia. RefSeq - NM_001110403 RefSeq Peptide - NP_001103873 swissprot - Q1LY29 swissprot - Q6NYR4 swissprot - Q1LY27 swissprot - A0A0R4IVB0 ZFIN ID - ZDB-GENE-990415-92 Ensembl - ENSDARG00000068992

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
si:dkey-4p15.3 / HSPA8* / P11142* / P63017* / Heat shock cognate 71 kDa protein * / heat shock protein family A (Hsp70) member 8*	ENSDARG00000037403	94
hsc70 / heat shock cognate 70	ENSDARG00000012381	91
hspa5 / heat shock protein 5 / P11021* / heat shock protein family A (Hsp70) member 5*	ENSDARG00000103846	62
hspa14 / Q5RGE6 / heat shock protein 14 / Q0VDF9* / Q99M31* / Heat shock 70 kDa protein 14 * / heat shock protein family A (Hsp70) member 14*	ENSDARG00000058030	26

Protein motifs (from Interpro)

Interpro ID	Name
IPR013126	Heat shock protein 70 family
IPR018181	Heat shock protein 70, conserved site
IPR029047	Heat shock protein 70kD, peptide-binding domain superfamily
IPR029048	Heat shock protein 70kD, C-terminal domain superfamily

Gene Ontology (GO)

Pathways (from Reactome)

Pathway description

Regulation of HSF1-mediated heat shock response

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000008	brain	brain necrotic , abnormal	Show
ZFA:0000012	central nervous system	central nervous system necrotic , abnormal	Show
ZFA:0000029	hindbrain	hindbrain decreased size , abnormal hindbrain quality , abnormal	Show
ZFA:0000042	midbrain hindbrain boundary	midbrain hindbrain boundary quality , abnormal midbrain hindbrain boundary condensed , abnormal	Show
ZFA:0000084	yolk	yolk circular , abnormal	Show
ZFA:0000095	pharyngeal arch 3-7 skeleton	pharyngeal arch 3-7 skeleton aplastic , abnormal	Show
ZFA:0000106	extension	extension decreased thickness , abnormal	Show
ZFA:0000107	eye	eye decreased size , abnormal	Show
ZFA:0000110	fourth ventricle	fourth ventricle distended , abnormal	Show
ZFA:0000112	gut	gut quality , abnormal gut hypoplastic , abnormal	Show
ZFA:0000123	liver	liver quality , abnormal liver hypoplastic , abnormal	Show
ZFA:0000396	nervous system	nervous system apoptotic , abnormal	Show
ZFA:0000737	cranium	cranium morphology , abnormal	Show
ZFA:0001114	head	head decreased size , abnormal	Show
ZFA:0001115	trunk	trunk decreased thickness , abnormal	Show
ZFA:0001205	Meckel s cartilage	Meckels cartilage deformed , abnormal	Show
ZFA:0001400	ceratohyal cartilage	ceratohyal cartilage deformed , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr