ENSDARG00000069463


Danio rerio

Features
Gene ID: ENSDARG00000069463
  
Biological name :alox12
  
Synonyms : alox12 / arachidonate 12-lipoxygenase
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 26029672
Gene end: 26047946
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000091900
NCBI entrez gene - 322732     See in Manteia.
RefSeq - NM_199618
RefSeq Peptide - NP_955912
swissprot - Q7T2A9
ZFIN ID - ZDB-GENE-030131-1452
Ensembl - ENSDARG00000069463
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
alox5a / arachidonate 5-lipoxygenase a / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000005727344
alox5b.3 / arachidonate 5-lipoxygenase b, tandem duplicate 3 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000006996643
alox5b.2 / arachidonate 5-lipoxygenase b, tandem duplicate 2 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000004308941
si:dkey-17e16.9 / ALOX12* / P18054* / P39654* / P39655* / P55249* / ALOX15* / P16050* / Alox12e* / arachidonate 12-lipoxygenase* / arachidonate 15-lipoxygenase* / arachidonate lipoxygenase,...ENSDARG0000007378139
alox5b.1 / arachidonate 5-lipoxygenase b, tandem duplicate 1 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000004308539
zgc:152891 / Alox8* / ALOXE3* / O15296* / O35936* / O70582* / O75342* / Q9BYJ1* / Q9WV07* / ALOX12B* / ALOX15B* / arachidonate lipoxygenase 3* / Arachidonate 8S-lipoxygenase * / arachidonat...ENSDARG0000001678936


Protein motifs (from Interpro)
Interpro ID Name
 IPR000907  Lipoxygenase
 IPR001024  PLAT/LH2 domain
 IPR001885  Lipoxygenase, mammalian
 IPR013819  Lipoxygenase, C-terminal
 IPR020834  Lipoxygenase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IDA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0004052 arachidonate 12-lipoxygenase activity IMP
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
Show

 ZFA:0000035 lens lens composition , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
Show

 ZFA:0000101 diencephalon diencephalon decreased size , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye decreased diameter , abnormal
Show

 ZFA:0000128 midbrain midbrain decreased size , abnormal
Show

 ZFA:0000155 somite somite unstructured , abnormal
Show

 ZFA:0001114 head head hypoplastic , abnormal
Show

 ZFA:0001117 post-vent region post-vent region bent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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