ENSDARG00000070485


Danio rerio

Features
Gene ID: ENSDARG00000070485
  
Biological name :cenps
  
Synonyms : cenps / centromere protein S
  
Possible biological names infered from orthology : CENPS-CORT / CENPS-CORT readthrough / Q8N2Z9 / Q9D084
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 45934682
Gene end: 45937000
  
Corresponding Affymetrix probe sets: Dr.13740.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000094265
NCBI entrez gene - 569270     See in Manteia.
RefSeq - NM_001128749
RefSeq Peptide - NP_001122221
swissprot - B3DJV8
ZFIN ID - ZDB-GENE-080723-52
Ensembl - ENSDARG00000070485
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CENPSENSGALG00000024481Gallus gallus
 CENPSENSG00000175279Homo sapiens
 CENPS-CORTENSG00000251503Homo sapiens
 CenpsENSMUSG00000073705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009072  Histone-fold
 IPR029003  CENP-S/Mhf1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000712 resolution of meiotic recombination intermediates IBA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0031297 replication fork processing IBA
 biological_processGO:0036297 interstrand cross-link repair IBA
 biological_processGO:0051382 kinetochore assembly IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0043240 Fanconi anaemia nuclear complex IBA
 cellular_componentGO:0071821 FANCM-MHF complex IBA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Fanconi Anemia Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000070485 cenps / centromere protein S / Q8N2Z9* / Q9D084* / CENPS-CORT* / CENPS-CORT readthrough*  / complex
 ENSDARG00000089291 cenpx / centromere protein X / A8MT69*  / complex






 

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contact: otassy@igbmc.fr