ENSDARG00000071076


Danio rerio

Features
Gene ID: ENSDARG00000071076
  
Biological name :ldhbb
  
Synonyms : lactate dehydrogenase Bb / ldhbb / Q6DGK2
  
Possible biological names infered from orthology : lactate dehydrogenase B / LDHB / L-lactate dehydrogenase B chain / P07195 / P16125
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 3326885
Gene end: 3336587
  
Corresponding Affymetrix probe sets: Dr.17515.1.A1_at (Zebrafish Array)   NM_001002474_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000095636
Ensembl peptide - ENSDARP00000154861
Ensembl peptide - ENSDARP00000120276
Ensembl peptide - ENSDARP00000118106
NCBI entrez gene - 436747     See in Manteia.
RefSeq - NM_001002474
RefSeq - XM_005170658
RefSeq - XM_021470477
RefSeq Peptide - NP_001002474
swissprot - E9QH54
swissprot - E9QGA6
swissprot - B2GRW6
swissprot - Q6DGK2
ZFIN ID - ZDB-GENE-040718-176
Ensembl - ENSDARG00000071076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LDHBENSGALG00000035836Gallus gallus
 LDHBENSG00000111716Homo sapiens
 LdhbENSMUSG00000030246Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ldhba / Q9PVK4 / lactate dehydrogenase Ba / LDHB* / P07195* / P16125* / lactate dehydrogenase B* / L-lactate dehydrogenase B chain *ENSDARG0000001964489
ldha / Q9PVK5 / lactate dehydrogenase A4 / LDHC* / P07864* / Q9BYZ2* / P00338* / P00342* / P06151* / Q6ZMR3* / LDHAL6A* / LDHAL6B* / lactate dehydrogenase C* / lactate dehydrogenase A* / la...ENSDARG0000010125172
uevld / Q6DBY5 / UEV and lactate/malate dehyrogenase domains / Q3U1V6* / Q8IX04*ENSDARG0000000926632


Protein motifs (from Interpro)
Interpro ID Name
 IPR001236  Lactate/malate dehydrogenase, N-terminal
 IPR001557  L-lactate/malate dehydrogenase
 IPR011304  L-lactate dehydrogenase
 IPR015955  Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
 IPR016040  NAD(P)-binding domain
 IPR018177  L-lactate dehydrogenase, active site
 IPR022383  Lactate/malate dehydrogenase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0019752 carboxylic acid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004459 L-lactate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000019644 ldhba / Q9PVK4 / lactate dehydrogenase Ba / LDHB* / P07195* / P16125* / lactate dehydrogenase B* / L-lactate dehydrogenase B chain *  / complex
 ENSDARG00000071076 ldhbb / Q6DGK2 / lactate dehydrogenase Bb / LDHB* / P07195* / P16125* / lactate dehydrogenase B* / L-lactate dehydrogenase B chain *  / complex
 ENSDARG00000101251 ldha / Q9PVK5 / lactate dehydrogenase A4 / LDHC* / P07864* / Q9BYZ2* / P00338* / P00342* / P06151* / Q6ZMR3* / LDHAL6A* / LDHAL6B* / lactate dehydrogenase C* / lactate dehydrogenase A* / la...  / complex






 

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