ENSDARG00000071566


Danio rerio

Features
Gene ID: ENSDARG00000071566
  
Biological name :ppp1cab
  
Synonyms : ppp1cab / protein phosphatase 1, catalytic subunit, alpha isozyme b
  
Possible biological names infered from orthology : P36873 / P63087 / PPP1CC / protein phosphatase 1 catalytic subunit gamma / Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 13205955
Gene end: 13223449
  
Corresponding Affymetrix probe sets: Dr.3477.1.S1_at (Zebrafish Array)   NM_212710_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000087338
NCBI entrez gene - 327301     See in Manteia.
RefSeq - NM_212710
RefSeq Peptide - NP_997875
swissprot - Q7ZVR3
ZFIN ID - ZDB-GENE-030131-5512
Ensembl - ENSDARG00000071566
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPP1CCENSGALG00000004571Gallus gallus
 P36873ENSG00000186298Homo sapiens
 P63087ENSMUSG00000004455Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppp1caa / protein phosphatase 1, catalytic subunit, alpha isozyme a / P62137* / PPP1CA* / P62136* / protein phosphatase 1 catalytic subunit alpha* / protein phosphatase 1, catalytic subunit...ENSDARG0000000348694
PPP1CC / protein phosphatase 1 catalytic subunit gamma / P36873*ENSDARG0000009922689
ppp1cb / protein phosphatase 1, catalytic subunit, beta isozymeENSDARG0000004415382
ppp1cbl / protein phosphatase 1, catalytic subunit, beta isoform, likeENSDARG0000010201263


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR029052  Metallo-dependent phosphatase-like
 IPR031675  Serine-threonine protein phosphatase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0006470 protein dephosphorylation IEA
 cellular_componentGO:0000164 protein phosphatase type 1 complex IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain distended , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
Show

 ZFA:0001094 whole organism whole organism malformed , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased functionality , abnormal
intersegmental vessel dilated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr