ENSDARG00000074597


Danio rerio

Features
Gene ID: ENSDARG00000074597
  
Biological name :lzts2a
  
Synonyms : leucine zipper, putative tumor suppressor 2a / lzts2a
  
Possible biological names infered from orthology : Leucine zipper putative tumor suppressor 2 / leucine zipper tumor suppressor 2 / LZTS2 / Q91YU6 / Q9BRK4
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 18801094
Gene end: 18863680
  
Corresponding Affymetrix probe sets: Dr.18084.1.A1_at (Zebrafish Array)   Dr.4392.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000101957
Ensembl peptide - ENSDARP00000122442
Ensembl peptide - ENSDARP00000115209
NCBI entrez gene - 570926     See in Manteia.
RefSeq - NM_001145606
RefSeq Peptide - NP_001139078
swissprot - B8A6E8
swissprot - B8A6E7
swissprot - A0A288CG34
ZFIN ID - ZDB-GENE-090313-276
Ensembl - ENSDARG00000074597
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LZTS2ENSGALG00000023612Gallus gallus
 LZTS2ENSG00000107816Homo sapiens
 Lzts2ENSMUSG00000035342Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lzts2b / leucine zipper, putative tumor suppressor 2b / LZTS2* / Q9BRK4* / leucine zipper tumor suppressor 2*ENSDARG0000007720748
lzts1 / leucine zipper, putative tumor suppressor 1 / P60853* / Q9Y250* / leucine zipper tumor suppressor 1*ENSDARG0000007556532
lzts3a / leucine zipper, putative tumor suppressor family member 3a / LZTS3* / O60299* / leucine zipper tumor suppressor family member 3*ENSDARG0000009875129
lzts3b / leucine zipper, putative tumor suppressor family member 3b / LZTS3* / A2AHG0* / O60299* / Leucine zipper putative tumor suppressor 3 * / leucine zipper tumor suppressor family member 3*ENSDARG0000005855828
n4bp3 / NEDD4 binding protein 3 / O15049* / Q8C7U1*ENSDARG0000006000721


Protein motifs (from Interpro)
Interpro ID Name
 IPR028597  Leucine zipper putative tumour suppressor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000910 cytokinesis IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IMP
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0051013 microtubule severing IEA
 biological_processGO:0051168 nuclear export IEA
 biological_processGO:0051255 spindle midzone assembly IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060026 convergent extension IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030496 midbody IEA
 molecular_functionGO:0008013 beta-catenin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000071 shield shield increased thickness , abnormal
Show

 ZFA:0000092 axis axis anterior-posterior axis elongated , abnormal
axis anterior-posterior axis shortened , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0001058 caudal fin caudal fin kinked , abnormal
caudal fin shortened , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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