ENSG00000107816


Homo sapiens

Features
Gene ID: ENSG00000107816
  
Biological name :LZTS2
  
Synonyms : leucine zipper tumor suppressor 2 / LZTS2 / Q9BRK4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.31
Gene start: 100996618
Gene end: 101007836
  
Corresponding Affymetrix probe sets: 1555881_s_at (Human Genome U133 Plus 2.0 Array)   224473_x_at (Human Genome U133 Plus 2.0 Array)   225013_at (Human Genome U133 Plus 2.0 Array)   232129_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402042
Ensembl peptide - ENSP00000359243
Ensembl peptide - ENSP00000407713
Ensembl peptide - ENSP00000474819
Ensembl peptide - ENSP00000416972
Ensembl peptide - ENSP00000359240
NCBI entrez gene - 84445     See in Manteia.
OMIM - 610454
RefSeq - XM_017016781
RefSeq - NM_001318099
RefSeq - NM_001318100
RefSeq - NM_001318101
RefSeq - NM_032429
RefSeq - XM_005270222
RefSeq - XM_017016780
RefSeq Peptide - NP_115805
RefSeq Peptide - NP_001305029
RefSeq Peptide - NP_001305030
RefSeq Peptide - NP_001305028
swissprot - S4R3W7
swissprot - B1AL11
swissprot - B1AL13
swissprot - B1AL12
swissprot - Q9BRK4
Ensembl - ENSG00000107816
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lzts2aENSDARG00000074597Danio rerio
 lzts2bENSDARG00000077207Danio rerio
 LZTS2ENSGALG00000023612Gallus gallus
 Lzts2ENSMUSG00000035342Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LZTS1 / Q9Y250 / leucine zipper tumor suppressor 1ENSG0000006133737
LZTS3 / O60299 / leucine zipper tumor suppressor family member 3ENSG0000008889932
N4BP3 / O15049 / NEDD4 binding protein 3ENSG0000014591124


Protein motifs (from Interpro)
Interpro ID Name
 IPR028597  Leucine zipper putative tumour suppressor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0072001 renal system development IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1900181 negative regulation of protein localization to nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0031982 vesicle IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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