ENSDARG00000074661


Danio rerio

Features
Gene ID: ENSDARG00000074661
  
Biological name :gper1
  
Synonyms : B3G515 / gper1 / G protein-coupled estrogen receptor 1
  
Possible biological names infered from orthology : Q8BMP4 / Q99527
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 45756605
Gene end: 45770089
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000156576
Ensembl peptide - ENSDARP00000070486
NCBI entrez gene - 565271     See in Manteia.
RefSeq - NM_001128723
RefSeq - XM_009299734
RefSeq Peptide - NP_001122195
swissprot - B3G515
ZFIN ID - ZDB-GENE-090311-1
Ensembl - ENSDARG00000074661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPER1ENSGALG00000004064Gallus gallus
 GPER1ENSG00000164850Homo sapiens
 Gper1ENSMUSG00000053647Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gpr146 / G protein-coupled receptor 146 / Q96CH1* / Q99LE2*ENSDARG0000005961011


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007420 brain development IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway IBA
 biological_processGO:0040019 positive regulation of embryonic development IMP
 biological_processGO:0043524 negative regulation of neuron apoptotic process IDA
 biological_processGO:0043950 positive regulation of cAMP-mediated signaling IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0051447 negative regulation of meiotic cell cycle IDA
 biological_processGO:0071392 cellular response to estradiol stimulus IDA
 biological_processGO:1900194 negative regulation of oocyte maturation IDA
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0032591 dendritic spine membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA
 molecular_functionGO:0005496 steroid binding IDA
 molecular_functionGO:0030284 estrogen receptor activity IDA
 molecular_functionGO:1990239 steroid hormone binding ISS


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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