ENSDARG00000075111


Danio rerio

Features
Gene ID: ENSDARG00000075111
  
Biological name :als2a
  
Synonyms : als2a / amyotrophic lateral sclerosis 2a (juvenile)
  
Possible biological names infered from orthology : ALS2 / ALS2, alsin Rho guanine nucleotide exchange factor / Alsin / Q920R0 / Q96Q42
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 13628635
Gene end: 13672200
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000097741
Ensembl peptide - ENSDARP00000105175
Ensembl peptide - ENSDARP00000114054
Ensembl peptide - ENSDARP00000118825
NCBI entrez gene - 557014     See in Manteia.
swissprot - F1Q9S9
swissprot - F1QQ22
swissprot - F1QS60
swissprot - F1QXR1
ZFIN ID - ZDB-GENE-070402-2
Ensembl - ENSDARG00000075111
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALS2ENSGALG00000008415Gallus gallus
 ALS2ENSG00000003393Homo sapiens
 Als2ENSMUSG00000026024Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
als2b / amyotrophic lateral sclerosis 2b (juvenile) / ALS2* / Alsin * / Q920R0* / Q96Q42* / ALS2, alsin Rho guanine nucleotide exchange factor*ENSDARG0000007692457
rsph10b / radial spoke head 10 homolog B / P0C881* / B2RC85* / RSPH10B2* / radial spoke head 10 homolog B2* / radial spoke head 10 homolog B (Chlamydomonas)*ENSDARG000000518916
morn3 / MORN repeat containing 3 / Q6PF18*ENSDARG000000216974
CT573248.2 / RSPH1* / Q8WYR4* / radial spoke head 1 homolog*ENSDARG000001022613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000408  Regulator of chromosome condensation, RCC1
 IPR001849  Pleckstrin homology domain
 IPR003123  VPS9 domain
 IPR003409  MORN motif
 IPR009091  Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr