ENSDARG00000076924


Danio rerio

Features
Gene ID: ENSDARG00000076924
  
Biological name :als2b
  
Synonyms : als2b / amyotrophic lateral sclerosis 2b (juvenile)
  
Possible biological names infered from orthology : ALS2 / ALS2, alsin Rho guanine nucleotide exchange factor / Alsin / Q920R0 / Q96Q42
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 9793495
Gene end: 9861191
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000098244
Ensembl peptide - ENSDARP00000123908
NCBI entrez gene - 100318899     See in Manteia.
RefSeq - XM_002662296
swissprot - F1QIZ1
swissprot - F8W4K3
ZFIN ID - ZDB-GENE-080929-1
Ensembl - ENSDARG00000076924
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALS2ENSGALG00000008415Gallus gallus
 ALS2ENSG00000003393Homo sapiens
 Als2ENSMUSG00000026024Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
als2a / amyotrophic lateral sclerosis 2a (juvenile) / ALS2* / Alsin * / Q920R0* / Q96Q42* / ALS2, alsin Rho guanine nucleotide exchange factor*ENSDARG0000007511156
rsph10b / radial spoke head 10 homolog B / P0C881* / B2RC85* / RSPH10B2* / radial spoke head 10 homolog B2* / radial spoke head 10 homolog B (Chlamydomonas)*ENSDARG000000518915
CT573248.2 / RSPH1* / Q8WYR4* / radial spoke head 1 homolog*ENSDARG000001022613
morn3 / MORN repeat containing 3 / Q6PF18*ENSDARG000000216973


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000408  Regulator of chromosome condensation, RCC1
 IPR003123  VPS9 domain
 IPR003409  MORN motif
 IPR009091  Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000075 spinal cord spinal cord neuron decreased amount , abnormal
Show

 ZFA:0009052 motor neuron motor neuron axon mislocalised , abnormal
motor neuron neuron projection morphology , abnormal
motor neuron neuron projection decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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