ENSDARG00000075621


Danio rerio

Features
Gene ID: ENSDARG00000075621
  
Biological name :birc5a
  
Synonyms : baculoviral IAP repeat containing 5a / birc5a
  
Possible biological names infered from orthology : baculoviral IAP repeat containing 5 / Baculoviral IAP repeat-containing protein 5 / BIRC5 / O15392 / O70201
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 34429702
Gene end: 34435604
  
Corresponding Affymetrix probe sets: Dr.14671.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000101794
swissprot - F1QTF4
ZFIN ID - ZDB-GENE-030826-1
Ensembl - ENSDARG00000075621
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BIRC5ENSGALG00000008713Gallus gallus
 BIRC5ENSG00000089685Homo sapiens
 Birc5ENSMUSG00000017716Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
birc5b / baculoviral IAP repeat containing 5bENSDARG0000005565535


Protein motifs (from Interpro)
Interpro ID Name
 IPR001370  BIR repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0009966 regulation of signal transduction IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0022008 neurogenesis IMP
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043523 regulation of neuron apoptotic process IMP
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0048514 blood vessel morphogenesis IMP
 biological_processGO:0090307 mitotic spindle assembly IBA
 biological_processGO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
brain apoptotic , abnormal
brain decreased size , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart morphology , abnormal
heart decreased size , abnormal
heart necrotic , abnormal
Show

 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm angioblastic mesenchymal cell cellular motility , abnormal
Show

 ZFA:0001073 axial vasculature axial vasculature decreased diameter , abnormal
axial vasculature apoptotic , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism necrotic , abnormal
whole organism bent , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head motor neuron disorganized , abnormal
Show

 ZFA:0001115 trunk trunk curved dorsal , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0001135 neural tube neural tube apoptotic , abnormal
neural tube proliferative region decreased functionality , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
Show

 ZFA:0001286 caudal vein plexus caudal vein plexus morphology , abnormal
caudal vein plexus apoptotic , abnormal
caudal vein plexus proliferative region decreased functionality , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 neural crest cell decreased amount , abnormal
Show

 ZFA:0005004 aortic arch aortic arch hypoplastic , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel aplastic , abnormal
dorsal longitudinal anastomotic vessel morphology , abnormal
Show

 ZFA:0005032 optic vein optic vein morphology , abnormal
Show

 ZFA:0005035 subintestinal vein subintestinal vein aplastic , abnormal
Show

 ZFA:0005054 inner optic circle inner optic circle morphology , abnormal
Show

 ZFA:0005061 ventricular myocardium ventricular myocardium decreased thickness , abnormal
Show

 ZFA:0005064 atrioventricular valve atrioventricular valve amorphous , abnormal
Show

 ZFA:0005072 endocardial ring endocardial ring amorphous , abnormal
Show

 ZFA:0007037 posterior neural tube posterior neural tube apoptotic , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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