ENSDARG00000075641


Danio rerio

Features
Gene ID: ENSDARG00000075641
  
Biological name :steap3
  
Synonyms : steap3 / STEAP family member 3, metalloreductase
  
Possible biological names infered from orthology : Q658P3 / STEAP3 metalloreductase / STEAP family member 3
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 890536
Gene end: 899861
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000122155
NCBI entrez gene - 100320152     See in Manteia.
RefSeq - XM_002663293
swissprot - E7F9Y0
ZFIN ID - ZDB-GENE-081104-268
Ensembl - ENSDARG00000075641
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STEAP3ENSGALG00000012117Gallus gallus
 Q658P3ENSG00000115107Homo sapiens
 Steap3ENSMUSG00000026389Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
steap2 / STEAP family member 2, metalloreductase / Q8BWB6* / Q8NFT2* / STEAP2 metalloreductase* / six transmembrane epithelial antigen of prostate 2*ENSDARG0000006288748
steap4 / STEAP family member 4 / Q923B6* / Q687X5* / STEAP4 metalloreductase* / Metalloreductase STEAP4 *ENSDARG0000005590141


Protein motifs (from Interpro)
Interpro ID Name
 IPR013130  Ferric reductase transmembrane component-like domain
 IPR016040  NAD(P)-binding domain
 IPR028939  Pyrroline-5-carboxylate reductase, catalytic, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015677 copper ion import IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098706 ferric iron import across plasma membrane IBA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008823 cupric reductase activity IBA
 molecular_functionGO:0052851 ferric-chelate reductase (NADPH) activity IBA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Transferrin endocytosis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000025468 bnip3la / BCL2 interacting protein 3 like a / BNIP3L* / O60238* / BCL2 interacting protein 3 like*  / reaction / complex






 

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