ENSDARG00000062887


Danio rerio

Features
Gene ID: ENSDARG00000062887
  
Biological name :steap2
  
Synonyms : steap2 / STEAP family member 2, metalloreductase
  
Possible biological names infered from orthology : Q8BWB6 / Q8NFT2 / six transmembrane epithelial antigen of prostate 2 / STEAP2 metalloreductase
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 31832458
Gene end: 31846366
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127717
Ensembl peptide - ENSDARP00000144675
NCBI entrez gene - 100151287     See in Manteia.
swissprot - E7FFL9
ZFIN ID - ZDB-GENE-131121-79
Ensembl - ENSDARG00000062887
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STEAP2ENSGALG00000009017Gallus gallus
 Q8NFT2ENSG00000157214Homo sapiens
 Q8BWB6ENSMUSG00000015653Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
steap3 / STEAP family member 3, metalloreductase / Q658P3* / STEAP family member 3* / STEAP3 metalloreductase*ENSDARG0000007564147
steap4 / STEAP family member 4 / Q923B6* / Q687X5* / STEAP4 metalloreductase* / Metalloreductase STEAP4 *ENSDARG0000005590139


Protein motifs (from Interpro)
Interpro ID Name
 IPR013130  Ferric reductase transmembrane component-like domain
 IPR016040  NAD(P)-binding domain
 IPR028939  Pyrroline-5-carboxylate reductase, catalytic, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015677 copper ion import IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098706 ferric iron import across plasma membrane IBA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008823 cupric reductase activity IBA
 molecular_functionGO:0052851 ferric-chelate reductase (NADPH) activity IBA


Pathways (from Reactome)
Pathway description
Transferrin endocytosis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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