ENSMUSG00000015653


Mus musculus

Features
Gene ID: ENSMUSG00000015653
  
Biological name :Steap2
  
Synonyms : Q8BWB6 / six transmembrane epithelial antigen of prostate 2 / Steap2
  
Possible biological names infered from orthology : Q8NFT2 / STEAP2 metalloreductase
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: A1
Gene start: 5664829
Gene end: 5694578
  
Corresponding Affymetrix probe sets: 10528008 (MoGene1.0st)   1428636_at (Mouse Genome 430 2.0 Array)   1438773_at (Mouse Genome 430 2.0 Array)   1442359_at (Mouse Genome 430 2.0 Array)   1444290_at (Mouse Genome 430 2.0 Array)   1446071_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000111087
Ensembl peptide - ENSMUSP00000111086
Ensembl peptide - ENSMUSP00000116910
Ensembl peptide - ENSMUSP00000132501
Ensembl peptide - ENSMUSP00000015797
Ensembl peptide - ENSMUSP00000111084
Ensembl peptide - ENSMUSP00000111085
NCBI entrez gene - 74051     See in Manteia.
MGI - MGI:1921301
RefSeq - XM_011240675
RefSeq - NM_001103156
RefSeq - NM_001103157
RefSeq - NM_001285469
RefSeq - NM_001285470
RefSeq - NM_001285471
RefSeq - NM_028734
RefSeq - XM_006503609
RefSeq Peptide - NP_001272399
RefSeq Peptide - NP_001272400
RefSeq Peptide - NP_083010
RefSeq Peptide - NP_001096626
RefSeq Peptide - NP_001096627
RefSeq Peptide - NP_001272398
swissprot - Q8BWB6
swissprot - D3Z1C4
swissprot - D3YUM6
swissprot - B2RX33
Ensembl - ENSMUSG00000015653
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 steap2ENSDARG00000062887Danio rerio
 STEAP2ENSGALG00000009017Gallus gallus
 Q8NFT2ENSG00000157214Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Steap3 / STEAP family member 3 / Q658P3* / STEAP3 metalloreductase*ENSMUSG0000002638953
Q923B6 / Steap4 / Metalloreductase STEAP4 / Q687X5* / STEAP4 metalloreductase*ENSMUSG0000001242844
Steap1 / Q9CWR7 / Metalloreductase STEAP1 / Q9UHE8* / Q6NZ63* / STEAP1B* / STEAP family member 1* / STEAP family member 1B*ENSMUSG0000001565231


Protein motifs (from Interpro)
Interpro ID Name
 IPR013130  Ferric reductase transmembrane component-like domain
 IPR028939  Pyrroline-5-carboxylate reductase, catalytic, N-terminal
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006893 Golgi to plasma membrane transport ISO
 biological_processGO:0006897 endocytosis ISO
 biological_processGO:0009725 response to hormone ISS
 biological_processGO:0015677 copper ion import IDA
 biological_processGO:0045055 regulated exocytosis ISS
 biological_processGO:0055072 iron ion homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IDA
 biological_processGO:0098706 ferric iron import across plasma membrane IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030140 trans-Golgi network transport vesicle ISS
 cellular_componentGO:0030173 integral component of Golgi membrane ISO
 molecular_functionGO:0005215 transporter activity ISS
 molecular_functionGO:0008823 cupric reductase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0052851 ferric-chelate reductase (NADPH) activity IDA


Pathways (from Reactome)
Pathway description
Transferrin endocytosis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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