ENSDARG00000075867


Danio rerio

Features
Gene ID: ENSDARG00000075867
  
Biological name :mkl1a
  
Synonyms : megakaryoblastic leukemia (translocation) 1a / mkl1a
  
Possible biological names infered from orthology : megakaryoblastic leukemia (translocation) 1 / MKL1 / MKL/myocardin-like protein 1 / Q8K4J6 / Q969V6
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 24708685
Gene end: 24765127
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128445
Ensembl peptide - ENSDARP00000145467
NCBI entrez gene - 797480     See in Manteia.
RefSeq - XM_009299400
RefSeq - XM_009299401
RefSeq - XM_021471421
swissprot - X1WDZ5
ZFIN ID - ZDB-GENE-121205-3
Ensembl - ENSDARG00000075867
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MKL1ENSGALG00000012024Gallus gallus
 MKL1ENSG00000196588Homo sapiens
 Mkl1ENSMUSG00000042292Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mkl1b / megakaryoblastic leukemia (translocation) 1b / MKL1* / Q8K4J6* / Q969V6* / MKL/myocardin-like protein 1 * / megakaryoblastic leukemia (translocation) 1*ENSDARG0000007622944
mkl2a / MKL/myocardin-like 2a / MKL2* / Q9ULH7* / MKL1/myocardin like 2*ENSDARG0000008830732
mkl2b / MKL/myocardin-like 2b / MKL2* / Q9ULH7* / MKL1/myocardin like 2*ENSDARG0000007686729
si:dkeyp-69b9.3 / MYOCD* / Q8IZQ8* / Q8VIM5* / myocardin*ENSDARG0000008888112


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR004018  RPEL repeat
 IPR029992  MKL/myocardin-like protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0010735 positive regulation of transcription via serum response element binding IEA
 biological_processGO:0051145 smooth muscle cell differentiation IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0003785 actin monomer binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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