ENSDARG00000077533


Danio rerio

Features
Gene ID: ENSDARG00000077533
  
Biological name :eif3f
  
Synonyms : eif3f / eukaryotic translation initiation factor 3, subunit F
  
Possible biological names infered from orthology : O00303 / Q9DCH4
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 10297027
Gene end: 10304044
  
Corresponding Affymetrix probe sets: Dr.5392.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000127037
NCBI entrez gene - 557270     See in Manteia.
RefSeq - NM_001200009
RefSeq Peptide - NP_001186938
swissprot - R4GEX4
ZFIN ID - ZDB-GENE-100215-2
Ensembl - ENSDARG00000077533
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000005326Gallus gallus
 EIF3FENSG00000175390Homo sapiens
 Eif3fENSMUSG00000031029Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
psmd7 / proteasome 26S subunit, non-ATPase 7 / P26516* / P51665* / proteasome (prosome, macropain) 26S subunit, non-ATPase, 7*ENSDARG0000010241727


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR024969  Rpn11/EIF3F, C-terminal
 IPR027531  Eukaryotic translation initiation factor 3 subunit F


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IBA
 biological_processGO:1904888 cranial skeletal system development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IEA
 cellular_componentGO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m IBA
 molecular_functionGO:0003743 translation initiation factor activity IBA
 molecular_functionGO:0031369 translation initiation factor binding IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000155 somite somite fused with somite , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001117 post-vent region post-vent region curled , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage morphology , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton decreased size , abnormal
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 ZFA:0001405 ethmoid cartilage ethmoid cartilage shape , abnormal
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 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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