ENSDARG00000078139


Danio rerio

Features
Gene ID: ENSDARG00000078139
  
Biological name :appl2
  
Synonyms : adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 / appl2
  
Possible biological names infered from orthology : adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 / DCC-interacting protein 13-beta / Q8K3G9 / Q8NEU8
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 5790536
Gene end: 5815834
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000101503
NCBI entrez gene - 100000135     See in Manteia.
RefSeq - NM_001128075
RefSeq - XM_005174259
RefSeq Peptide - NP_001121547
swissprot - F1RB27
ZFIN ID - ZDB-GENE-081016-2
Ensembl - ENSDARG00000078139
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APPL2ENSGALG00000027122Gallus gallus
 APPL2ENSG00000136044Homo sapiens
 Appl2ENSMUSG00000020263Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
appl1 / hesx1 / adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 / Q9UKG1* / adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1*ENSDARG0000006073450


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005768 endosome IGI
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Recruitment of mitotic centrosome proteins and complexes
Recruitment of NuMA to mitotic centrosomes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000048 olfactory placode olfactory placode apoptotic , abnormal
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 ZFA:0000106 extension extension decreased size , abnormal
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 ZFA:0001094 whole organism whole organism apoptotic , abnormal
whole organism bent , abnormal
whole organism edematous , abnormal
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 ZFA:0001117 post-vent region post-vent region kinked , abnormal
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 ZFA:0001135 neural tube neural tube apoptotic , abnormal
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 ZFA:0001149 olfactory system olfactory system apoptotic , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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