ENSG00000136044


Homo sapiens

Features
Gene ID: ENSG00000136044
  
Biological name :APPL2
  
Synonyms : adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 / APPL2 / Q8NEU8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q23.3
Gene start: 105173296
Gene end: 105236238
  
Corresponding Affymetrix probe sets: 218218_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449767
Ensembl peptide - ENSP00000448569
Ensembl peptide - ENSP00000449410
Ensembl peptide - ENSP00000258530
Ensembl peptide - ENSP00000444472
Ensembl peptide - ENSP00000446510
Ensembl peptide - ENSP00000446917
Ensembl peptide - ENSP00000447520
Ensembl peptide - ENSP00000447828
NCBI entrez gene - 55198     See in Manteia.
OMIM - 606231
RefSeq - XM_017019554
RefSeq - NM_001251904
RefSeq - NM_001251905
RefSeq - NM_018171
RefSeq - XM_006719472
RefSeq - XM_011538530
RefSeq - XM_011538531
RefSeq - XM_011538532
RefSeq - XM_017019551
RefSeq - XM_017019552
RefSeq - XM_017019553
RefSeq Peptide - NP_001238834
RefSeq Peptide - NP_060641
RefSeq Peptide - NP_001238833
swissprot - F8W124
swissprot - H0YH86
swissprot - F8VS86
swissprot - Q8NEU8
swissprot - F8VR68
swissprot - F8VWV2
swissprot - F8VXB0
Ensembl - ENSG00000136044
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 appl2ENSDARG00000078139Danio rerio
 APPL2ENSGALG00000027122Gallus gallus
 Appl2ENSMUSG00000020263Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
APPL1 / Q9UKG1 / adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1ENSG0000015750052


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008283 cell proliferation IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016581 NuRD complex IDA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr