ENSDARG00000079624


Danio rerio

Features
Gene ID: ENSDARG00000079624
  
Biological name :amer1
  
Synonyms : amer1 / APC membrane recruitment protein 1 / F1RDM5
  
Possible biological names infered from orthology : Q5JTC6 / Q7TS75
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 22011575
Gene end: 22019061
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000099285
NCBI entrez gene - 100885784     See in Manteia.
RefSeq - NM_001346277
RefSeq Peptide - NP_001333206
swissprot - F1RDM5
ZFIN ID - ZDB-GENE-070719-2
Ensembl - ENSDARG00000079624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AMER1ENSGALG00000007599Gallus gallus
 AMER1ENSG00000184675Homo sapiens
 Amer1ENSMUSG00000050332Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
amer2 / F1QGH6 / APC membrane recruitment protein 2 / Q8N7J2*ENSDARG0000007522214
si:dkey-231j24.3 / AMER3* / Q6NS69* / Q8N944* / APC membrane recruitment protein 3*ENSDARG0000009581913


Protein motifs (from Interpro)
Interpro ID Name
 IPR019003  APC membrane recruitment protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IGI
 biological_processGO:0048856 anatomical structure development IBA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway ISS
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway ISS
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0008013 beta-catenin binding ISS
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0001114 head head malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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