ENSGALG00000007599


Gallus gallus

Features
Gene ID: ENSGALG00000007599
  
Biological name :AMER1
  
Synonyms : AMER1 / APC membrane recruitment protein 1
  
Possible biological names infered from orthology : Q5JTC6 / Q7TS75
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 11720134
Gene end: 11723565
  
Corresponding Affymetrix probe sets: Gga.14959.1.S1_s_at (Chicken Array)   GgaAffx.21189.1.S1_at (Chicken Array)   GgaAffx.4744.1.S1_s_at (Chicken Array)   GgaAffx.4744.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038731
NCBI entrez gene - 422314     See in Manteia.
RefSeq - XM_004940779
RefSeq - XM_004940780
RefSeq - XM_015278574
swissprot - F1NGE5
Ensembl - ENSGALG00000007599
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amer1ENSDARG00000079624Danio rerio
 AMER1ENSG00000184675Homo sapiens
 Amer1ENSMUSG00000050332Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AMER2 / E1C2Q8 / APC membrane recruitment protein 2 / Q8N7J2*ENSGALG0000002786814
AMER3 / APC membrane recruitment protein 3 / Q6NS69* / Q8N944*ENSGALG0000004150112


Protein motifs (from Interpro)
Interpro ID Name
 IPR019003  APC membrane recruitment protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0048856 anatomical structure development IBA
 biological_processGO:0060348 bone development IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0072161 mesenchymal cell differentiation involved in kidney development IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1903364 positive regulation of cellular protein catabolic process IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:1904713 beta-catenin destruction complex binding IEA


Pathways (from Reactome)
Pathway description
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
Disassembly of the destruction complex and recruitment of AXIN to the membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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