ENSDARG00000086391


Danio rerio

Features
Gene ID: ENSDARG00000086391
  
Biological name :cald1b
  
Synonyms : cald1b / caldesmon 1b
  
Possible biological names infered from orthology : CALD1 / caldesmon 1 / Q05682
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 20140926
Gene end: 20211831
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000111675
Ensembl peptide - ENSDARP00000116803
NCBI entrez gene - 563892     See in Manteia.
RefSeq - NM_001320459
RefSeq Peptide - NP_001307388
swissprot - F1R0G7
swissprot - E7EZ62
ZFIN ID - ZDB-GENE-090313-229
Ensembl - ENSDARG00000086391
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CALD1ENSGALG00000033471Gallus gallus
 CALD1ENSG00000122786Homo sapiens
 Cald1ENSMUSG00000029761Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lsp1 / lymphocyte-specific protein 1ENSDARG0000002731023
CT030188.1ENSDARG0000009938516


Protein motifs (from Interpro)
Interpro ID Name
 IPR006017  Caldesmon
 IPR006018  Caldesmon/lymphocyte specific protein
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0006936 muscle contraction IEA
 biological_processGO:0043534 blood vessel endothelial cell migration IMP
 molecular_functionGO:0003779 actin binding IDA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0017022 myosin binding IEA
 molecular_functionGO:0032036 myosin heavy chain binding IDA


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle elongated , abnormal
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 ZFA:0000014 dorsal aorta dorsal aorta morphology , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000114 heart heart morphology , abnormal
heart contractility , abnormal
heart decreased functionality , abnormal
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 ZFA:0000471 atrium atrium increased size , abnormal
atrium elongated , abnormal
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 ZFA:0000477 posterior cardinal vein posterior cardinal vein morphology , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton morphology , abnormal
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 ZFA:0001267 cranial vasculature cranial vasculature morphology , abnormal
cranial vasculature dilated , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
intersegmental vessel decreased amount , abnormal
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 ZFA:0001286 caudal vein plexus caudal vein plexus decreased size , abnormal
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 ZFA:0005004 aortic arch aortic arch morphology , abnormal
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 ZFA:0005024 trunk vasculature trunk vasculature morphology , abnormal
trunk vasculature broken , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel aplastic , abnormal
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 ZFA:0005035 subintestinal vein subintestinal vein morphology , abnormal
subintestinal vein structure , abnormal
subintestinal vein decreased functionality , abnormal
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 ZFA:0005064 atrioventricular valve atrioventricular valve aplastic , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte aggregated , abnormal
nucleate erythrocyte fluid flow rate , abnormal
nucleate erythrocyte decreased amount , abnormal
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 ZFA:0009316 cardiac muscle cell cardiac muscle cell decreased size , abnormal
cardiac muscle cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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