ENSDARG00000086450


Danio rerio

Features
Gene ID: ENSDARG00000086450
  
Biological name :tdg.2
  
Synonyms : tdg.2 / thymine DNA glycosylase, tandem duplicate 2
  
Possible biological names infered from orthology : Mus musculus thymine DNA glycosylase (Tdg), transcript variant 3, mRNA. / P56581 / Q13569 / TDG / thymine DNA glycosylase
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 18953575
Gene end: 18965502
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127725
Ensembl peptide - ENSDARP00000128091
Ensembl peptide - ENSDARP00000105235
NCBI entrez gene - 558951     See in Manteia.
swissprot - E7F5Y8
swissprot - X1WBY3
swissprot - X1WCZ4
ZFIN ID - ZDB-GENE-131121-30
Ensembl - ENSDARG00000086450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TDGENSGALG00000031457Gallus gallus
 TDGENSG00000139372Homo sapiens
 TdgENSMUSG00000034674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tdg.1 / thymine DNA glycosylase, tandem duplicate 1 / TDG* / Q13569* / P56581* / thymine DNA glycosylase* / Mus musculus thymine DNA glycosylase (Tdg), transcript variant 3, mRNA.*ENSDARG0000001300453


Protein motifs (from Interpro)
Interpro ID Name
 IPR005122  Uracil-DNA glycosylase-like
 IPR015637  G/U mismatch-specific DNA glycosylase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006285 base-excision repair, AP site formation IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0004844 uracil DNA N-glycosylase activity IBA
 molecular_functionGO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity IBA
 molecular_functionGO:0019104 DNA N-glycosylase activity IEA


Pathways (from Reactome)
Pathway description
Cleavage of the damaged pyrimidine
Displacement of DNA glycosylase by APEX1
SUMOylation of DNA damage response and repair proteins
TET1,2,3 and TDG demethylate DNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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