ENSDARG00000090152


Danio rerio

Features
Gene ID: ENSDARG00000090152
  
Biological name :anapc10
  
Synonyms : anapc10 / anaphase promoting complex subunit 10
  
Possible biological names infered from orthology : Mus musculus anaphase promoting complex subunit 10 (Anapc10), transcript variant 4, mRNA. / Q8K2H6 / Q9UM13
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 43718115
Gene end: 43727050
  
Corresponding Affymetrix probe sets: Dr.14526.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000144483
Ensembl peptide - ENSDARP00000123807
Ensembl peptide - ENSDARP00000124965
NCBI entrez gene - 798352     See in Manteia.
RefSeq - NM_001267696
RefSeq - NM_001267697
RefSeq Peptide - NP_001254625
RefSeq Peptide - NP_001254626
swissprot - E7FCJ1
ZFIN ID - ZDB-GENE-060224-2
Ensembl - ENSDARG00000090152
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ANAPC10ENSGALG00000028643Gallus gallus
 Q9UM13ENSG00000164162Homo sapiens
 Q8K2H6ENSMUSG00000036977Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004939  APC10/DOC domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR016901  Anaphase-promoting complex subunit APC10/Doc1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IBA
 biological_processGO:1904668 positive regulation of ubiquitin protein ligase activity IBA
 cellular_componentGO:0005680 anaphase-promoting complex IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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