ENSMUSG00000036977


Mus musculus

Features
Gene ID: ENSMUSG00000036977
  
Biological name :Anapc10
  
Synonyms : Anapc10 / Mus musculus anaphase promoting complex subunit 10 (Anapc10), transcript variant 4, mRNA. / Q8K2H6
  
Possible biological names infered from orthology : anaphase promoting complex subunit 10 / Q9UM13
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C1
Gene start: 79711820
Gene end: 79779059
  
Corresponding Affymetrix probe sets: 10573048 (MoGene1.0st)   1429375_at (Mouse Genome 430 2.0 Array)   1429376_s_at (Mouse Genome 430 2.0 Array)   1458390_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048244
Ensembl peptide - ENSMUSP00000148220
NCBI entrez gene - 68999     See in Manteia.
MGI - MGI:1916249
RefSeq - XM_006531343
RefSeq - NM_001357236
RefSeq - NM_026904
RefSeq - XM_006531339
RefSeq - XM_006531340
RefSeq - XM_006531342
RefSeq Peptide - NP_001344163
RefSeq Peptide - NP_001344164
RefSeq Peptide - NP_001344165
RefSeq Peptide - NP_081180
swissprot - Q8K2H6
Ensembl - ENSMUSG00000036977
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anapc10ENSDARG00000090152Danio rerio
 ANAPC10ENSGALG00000028643Gallus gallus
 Q9UM13ENSG00000164162Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004939  APC10/DOC domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR016901  Anaphase-promoting complex subunit APC10/Doc1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 biological_processGO:1904668 positive regulation of ubiquitin protein ligase activity IBA
 cellular_componentGO:0005680 anaphase-promoting complex IBA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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