ENSDARG00000090912


Danio rerio

Features
Gene ID: ENSDARG00000090912
  
Biological name :npc2
  
Synonyms : Niemann-Pick disease, type C2 / npc2 / Q9DGJ3
  
Possible biological names infered from orthology : Epididymal secretory protein E1 / NPC intracellular cholesterol transporter 2 / P61916 / Q9Z0J0
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 43030317
Gene end: 43031828
  
Corresponding Affymetrix probe sets: Dr.4376.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000050398
Ensembl peptide - ENSDARP00000113663
NCBI entrez gene - 282673     See in Manteia.
RefSeq - NM_173224
RefSeq Peptide - NP_775331
swissprot - Q9DGJ3
ZFIN ID - ZDB-GENE-021206-13
Ensembl - ENSDARG00000090912
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NPC2ENSGALG00000010237Gallus gallus
 NPC2ENSG00000119655Homo sapiens
 Npc2ENSMUSG00000021242Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:193725 / NPC2 (1 of many) / NPC2* / P61916* / Q9Z0J0* / Epididymal secretory protein E1 * / NPC intracellular cholesterol transporter 2*ENSDARG0000009697991


Protein motifs (from Interpro)
Interpro ID Name
 IPR003172  MD-2-related lipid-recognition domain
 IPR014756  Immunoglobulin E-set
 IPR033916  ML domain, Npc2 like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0032367 intracellular cholesterol transport IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
LDL clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000017180 npc1 / Niemann-Pick disease, type C1 / O15118* / O35604* / Niemann-Pick C1 protein * / NPC intracellular cholesterol transporter 1*  / reaction






 

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