ENSDARG00000098375


Danio rerio

Features
Gene ID: ENSDARG00000098375
  
Biological name :polr1a
  
Synonyms : polr1a / polymerase (RNA) I polypeptide A
  
Possible biological names infered from orthology : DNA-directed RNA polymerase I subunit RPA1 / O35134 / O95602 / RNA polymerase I subunit A
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 16151368
Gene end: 16212896
  
Corresponding Affymetrix probe sets: Dr.12641.1.S1_at (Zebrafish Array)   Dr.770.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000130633
Ensembl peptide - ENSDARP00000136059
NCBI entrez gene - 327078     See in Manteia.
swissprot - A0A0R4I9V4
swissprot - A0A0R4IPG4
ZFIN ID - ZDB-GENE-030131-5286
Ensembl - ENSDARG00000098375
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLR1AENSGALG00000038160Gallus gallus
 O95602ENSG00000068654Homo sapiens
 O35134ENSMUSG00000049553Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000722  RNA polymerase, alpha subunit
 IPR006592  RNA polymerase, N-terminal
 IPR007066  RNA polymerase Rpb1, domain 3
 IPR007080  RNA polymerase Rpb1, domain 1
 IPR007081  RNA polymerase Rpb1, domain 5
 IPR007083  RNA polymerase Rpb1, domain 4
 IPR015699  DNA-directed RNA pol I, largest subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase I Transcription Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
Show

 ZFA:0000008 brain brain quality , abnormal
brain morphology , abnormal
brain decreased size , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000013 cranial ganglion cranial ganglion decreased size , abnormal
Show

 ZFA:0000029 hindbrain hindbrain hydrocephalic , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased thickness , abnormal
midbrain hindbrain boundary quality , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
yolk quality , abnormal
Show

 ZFA:0000106 extension extension decreased size , abnormal
extension decreased thickness , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye shape , abnormal
Show

 ZFA:0000217 inner ear inner ear decreased size , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism shape , abnormal
whole organism dead , abnormal
whole organism decreased size , abnormal
Show

 ZFA:0001114 head head flat , abnormal
head decreased size , abnormal
head shape , abnormal
Show

 ZFA:0001115 trunk trunk decreased thickness , abnormal
Show

 ZFA:0001117 post-vent region post-vent region shape , abnormal
post-vent region decreased length , abnormal
Show

 ZFA:0001135 neural tube neural tube apoptotic , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin decreased size , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton agenesis , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage absent , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage absent , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 decreased size , abnormal
pharyngeal arch 3-7 decreased amount , abnormal
Show

 ZFA:0009003 cranial neural crest cell cranial neural crest cell decreased amount , abnormal
Show

 ZFA:0009091 melanocyte melanocyte quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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