ENSDARG00000099458


Danio rerio

Features
Gene ID: ENSDARG00000099458
  
Biological name :ddx46
  
Synonyms : ddx46 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
  
Possible biological names infered from orthology : DEAD-box helicase 46 / Probable ATP-dependent RNA helicase DDX46 / Q569Z5 / Q7L014
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 45717930
Gene end: 45732177
  
Corresponding Affymetrix probe sets: Dr.1062.1.A1_at (Zebrafish Array)   Dr.25491.1.S1_at (Zebrafish Array)   NM_001024817_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000135125
NCBI entrez gene - 321948     See in Manteia.
RefSeq - NM_001024817
RefSeq Peptide - NP_001019988
swissprot - A0A0R4IL10
ZFIN ID - ZDB-GENE-030131-667
Ensembl - ENSDARG00000099458
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDX46ENSGALG00000006404Gallus gallus
 DDX46ENSG00000145833Homo sapiens
 Ddx46ENSMUSG00000021500Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic , abnormal
Show

 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm hematopoietic stem cell decreased distribution , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0000094 blood island blood island hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
Show

 ZFA:0000123 liver liver decreased size , abnormal
Show

 ZFA:0000152 retina retina decreased size , abnormal
retina apoptotic , abnormal
Show

 ZFA:0000706 posterior intestine posterior intestine apoptotic , abnormal
Show

 ZFA:0001078 thymus thymus lymphoid progenitor cell absent , abnormal
Show

 ZFA:0001114 head head quality , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased size , abnormal
Show

 ZFA:0005023 hematopoietic system hematopoietic system posterior region decreased amount , abnormal
Show

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta hematopoietic stem cell decreased distribution , abnormal
ventral wall of dorsal aorta hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0005124 intestinal epithelium intestinal epithelium decreased thickness , abnormal
intestinal epithelium smooth , abnormal
Show

 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased distribution , abnormal
hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0009325 erythroid lineage cell erythroid lineage cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr