ENSDARG00000099527


Danio rerio

Features
Gene ID: ENSDARG00000099527
  
Biological name :nkiras1
  
Synonyms : NFKB inhibitor interacting Ras-like 1 / nkiras1 / Q6DGQ1
  
Possible biological names infered from orthology : NF-kappa-B inhibitor-interacting Ras-like protein 1 / Q8CEC5 / Q9NYS0
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 17377346
Gene end: 17385548
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000135507
NCBI entrez gene - 100002175     See in Manteia.
RefSeq - NM_001100076
RefSeq Peptide - NP_001093546
swissprot - Q6DGQ1
ZFIN ID - ZDB-GENE-040718-215
Ensembl - ENSDARG00000099527
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NKIRAS1ENSGALG00000011289Gallus gallus
 Q9NYS0ENSG00000197885Homo sapiens
 Q8CEC5ENSMUSG00000021772Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nkiras2 / NFKB inhibitor interacting Ras-like 2 / Q9CR56* / Q9NYR9* / NF-kappa-B inhibitor-interacting Ras-like protein 2 *ENSDARG0000005259466


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
RIP-mediated NFkB activation via ZBP1
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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