ENSMUSG00000021772


Mus musculus

Features
Gene ID: ENSMUSG00000021772
  
Biological name :Nkiras1
  
Synonyms : NF-kappa-B inhibitor-interacting Ras-like protein 1 / Nkiras1 / Q8CEC5
  
Possible biological names infered from orthology : NFKB inhibitor interacting Ras like 1 / Q9NYS0
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: A2
Gene start: 18271136
Gene end: 18284003
  
Corresponding Affymetrix probe sets: 10412900 (MoGene1.0st)   1428503_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022294
Ensembl peptide - ENSMUSP00000121496
Ensembl peptide - ENSMUSP00000122235
NCBI entrez gene - 69721     See in Manteia.
MGI - MGI:1916971
RefSeq - XM_006518097
RefSeq - NM_001316711
RefSeq - NM_001316712
RefSeq - NM_023526
RefSeq Peptide - NP_001303640
RefSeq Peptide - NP_001303641
RefSeq Peptide - NP_076015
swissprot - F7BUB1
swissprot - F8WIJ8
swissprot - Q8CEC5
Ensembl - ENSMUSG00000021772
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DGQ1ENSDARG00000099527Danio rerio
 NKIRAS1ENSGALG00000011289Gallus gallus
 Q9NYS0ENSG00000197885Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CR56 / Nkiras2 / NF-kappa-B inhibitor-interacting Ras-like protein 2 / Q9NYR9* / NFKB inhibitor interacting Ras like 2*ENSMUSG0000001783770


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
RIP-mediated NFkB activation via ZBP1
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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