ENSMUSG00000017837


Mus musculus

Features
Gene ID: ENSMUSG00000017837
  
Biological name :Nkiras2
  
Synonyms : NF-kappa-B inhibitor-interacting Ras-like protein 2 / Nkiras2 / Q9CR56
  
Possible biological names infered from orthology : NFKB inhibitor interacting Ras like 2 / Q9NYR9
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 100619244
Gene end: 100627607
  
Corresponding Affymetrix probe sets: 10381162 (MoGene1.0st)   1424416_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000017981
Ensembl peptide - ENSMUSP00000059559
Ensembl peptide - ENSMUSP00000102999
Ensembl peptide - ENSMUSP00000114456
NCBI entrez gene - 71966     See in Manteia.
MGI - MGI:1919216
RefSeq - NM_028024
RefSeq - XM_017314775
RefSeq - XM_017314776
RefSeq Peptide - NP_082300
swissprot - F6XZA4
swissprot - Q9CR56
Ensembl - ENSMUSG00000017837
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkiras2ENSDARG00000052594Danio rerio
 Q5ZJW6ENSGALG00000028971Gallus gallus
 Q9NYR9ENSG00000168256Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8CEC5 / Nkiras1 / NF-kappa-B inhibitor-interacting Ras-like protein 1 / Q9NYS0* / NFKB inhibitor interacting Ras like 1*ENSMUSG0000002177271


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
RIP-mediated NFkB activation via ZBP1
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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