ENSG00000168256


Homo sapiens

Features
Gene ID: ENSG00000168256
  
Biological name :NKIRAS2
  
Synonyms : NFKB inhibitor interacting Ras like 2 / NKIRAS2 / Q9NYR9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.2
Gene start: 42011382
Gene end: 42025644
  
Corresponding Affymetrix probe sets: 218240_at (Human Genome U133 Plus 2.0 Array)   222105_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466135
Ensembl peptide - ENSP00000465633
Ensembl peptide - ENSP00000468081
Ensembl peptide - ENSP00000468245
Ensembl peptide - ENSP00000303580
Ensembl peptide - ENSP00000312773
Ensembl peptide - ENSP00000377458
Ensembl peptide - ENSP00000377459
Ensembl peptide - ENSP00000377463
Ensembl peptide - ENSP00000401976
Ensembl peptide - ENSP00000419929
Ensembl peptide - ENSP00000465588
NCBI entrez gene - 28511     See in Manteia.
OMIM - 604497
RefSeq - XM_005257251
RefSeq - NM_001001349
RefSeq - NM_001144927
RefSeq - NM_001144928
RefSeq - NM_001144929
RefSeq - NM_017595
RefSeq Peptide - NP_060065
RefSeq Peptide - NP_001138400
RefSeq Peptide - NP_001138401
RefSeq Peptide - NP_001001349
RefSeq Peptide - NP_001138399
swissprot - K7EKE9
swissprot - K7ELL8
swissprot - K7ERG2
swissprot - K7ER26
swissprot - Q9NYR9
swissprot - A0A024R1Z4
swissprot - A0A0A0MTA0
swissprot - H7BXP1
Ensembl - ENSG00000168256
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkiras2ENSDARG00000052594Danio rerio
 Q5ZJW6ENSGALG00000028971Gallus gallus
 Q9CR56ENSMUSG00000017837Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NYS0 / NKIRAS1 / NFKB inhibitor interacting Ras like 1ENSG0000019788570


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling NAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
RIP-mediated NFkB activation via ZBP1
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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