ENSG00000197885


Homo sapiens

Features
Gene ID: ENSG00000197885
  
Biological name :NKIRAS1
  
Synonyms : NFKB inhibitor interacting Ras like 1 / NKIRAS1 / Q9NYS0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p24.2
Gene start: 23891660
Gene end: 23946591
  
Corresponding Affymetrix probe sets: 225930_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415225
Ensembl peptide - ENSP00000483749
Ensembl peptide - ENSP00000373411
Ensembl peptide - ENSP00000392307
Ensembl peptide - ENSP00000393785
Ensembl peptide - ENSP00000394214
Ensembl peptide - ENSP00000396063
Ensembl peptide - ENSP00000400385
Ensembl peptide - ENSP00000406543
NCBI entrez gene - 28512     See in Manteia.
OMIM - 604496
RefSeq - NM_020345
RefSeq - XM_005265078
RefSeq - XM_005265076
RefSeq - XM_005265077
RefSeq Peptide - NP_065078
swissprot - G5E9P3
swissprot - Q9NYS0
Ensembl - ENSG00000197885
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DGQ1ENSDARG00000099527Danio rerio
 NKIRAS1ENSGALG00000011289Gallus gallus
 Q8CEC5ENSMUSG00000021772Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NYR9 / NKIRAS2 / NFKB inhibitor interacting Ras like 2ENSG0000016825669


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling NAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity NAS
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
RIP-mediated NFkB activation via ZBP1
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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