ENSDARG00000099579


Danio rerio

Features
Gene ID: ENSDARG00000099579
  
Biological name :aldh18a1
  
Synonyms : aldehyde dehydrogenase 18 family, member A1 / aldh18a1
  
Possible biological names infered from orthology : Delta-1-pyrroline-5-carboxylate synthase Glutamate 5-kinase Gamma-glutamyl phosphate reductase / P54886 / Q9Z110
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 30788912
Gene end: 30810171
  
Corresponding Affymetrix probe sets: Dr.1076.1.A1_at (Zebrafish Array)   Dr.7738.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000149534
Ensembl peptide - ENSDARP00000137162
NCBI entrez gene - 557186     See in Manteia.
RefSeq - NM_001083546
RefSeq - XM_009306786
RefSeq - XM_009306787
RefSeq Peptide - NP_001077015
swissprot - A4IGC8
ZFIN ID - ZDB-GENE-030131-5602
Ensembl - ENSDARG00000099579
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000034655Gallus gallus
 P54886ENSG00000059573Homo sapiens
 Q9Z110ENSMUSG00000025007Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000965  GPR domain
 IPR001048  Aspartate/glutamate/uridylate kinase
 IPR001057  Glutamate/acetylglutamate kinase
 IPR005715  Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase
 IPR005766  Delta l-pyrroline-5-carboxylate synthetase
 IPR015590  Aldehyde dehydrogenase domain
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR019797  Glutamate 5-kinase, conserved site
 IPR020593  Gamma-glutamyl phosphate reductase GPR, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006561 proline biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008652 cellular amino acid biosynthetic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0055129 L-proline biosynthetic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004349 glutamate 5-kinase activity IEA
 molecular_functionGO:0004350 glutamate-5-semialdehyde dehydrogenase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000099579 aldh18a1 / aldehyde dehydrogenase 18 family, member A1 / P54886* / Q9Z110* / Delta-1-pyrroline-5-carboxylate synthase Glutamate 5-kinase Gamma-glutamyl phosphate reductase*  / complex






 

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