ENSDARG00000100917


Danio rerio

Features
Gene ID: ENSDARG00000100917
  
Biological name :slc30a8
  
Synonyms : slc30a8 / solute carrier family 30 (zinc transporter), member 8
  
Possible biological names infered from orthology : Q8BGG0 / Q8IWU4 / solute carrier family 30 member 8 / Zinc transporter 8
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 46343385
Gene end: 46362232
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000133246
Ensembl peptide - ENSDARP00000148843
swissprot - A0A0R4IFM6
ZFIN ID - ZDB-GENE-060315-10
Ensembl - ENSDARG00000100917
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC30A8ENSGALG00000034377Gallus gallus
 Q8IWU4ENSG00000164756Homo sapiens
 Q8BGG0ENSMUSG00000022315Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slc30a2 / solute carrier family 30 (zinc transporter), member 2 / P97441* / Q99726* / SLC30A3* / solute carrier family 30 member 3* / Mus musculus solute carrier family 30 (zinc transporter...ENSDARG0000002130552
slc30a4 / solute carrier family 30 (zinc transporter), member 4 / O35149* / O14863* / Zinc transporter 4 * / solute carrier family 30 member 4*ENSDARG0000000718024
slc30a1b / solute carrier family 30 (zinc transporter), member 1b / Q9Y6M5* / Q60738* / SLC30A1* / solute carrier family 30 member 1* / solute carrier family 30 (zinc transporter), member 1*ENSDARG0000005389624
slc30a1a / solute carrier family 30 (zinc transporter), member 1a / Q9Y6M5* / Q60738* / SLC30A1* / solute carrier family 30 member 1* / solute carrier family 30 (zinc transporter), member 1*ENSDARG0000000546322
slc30a10 / solute carrier family 30, member 10 / Q6XR72*ENSDARG0000010398317
FO681288.1ENSDARG0000005458416


Protein motifs (from Interpro)
Interpro ID Name
 IPR002524  Cation efflux protein
 IPR027470  Cation efflux protein, cytoplasmic domain
 IPR033572  Zinc transporter 8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006829 zinc ion transport ISS
 biological_processGO:0006882 cellular zinc ion homeostasis IEA
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071577 zinc ion transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity IEA
 molecular_functionGO:0008324 cation transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Insulin processing
Zinc efflux and compartmentalization by the SLC30 family


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001260 endocrine pancreas endocrine pancreas increased distribution , abnormal
Show

 ZFA:0009102 pancreatic B cell pancreatic B cell decreased amount , abnormal
pancreatic B cell decreased area , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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