ENSDARG00000101576


Danio rerio

Features
Gene ID: ENSDARG00000101576
  
Biological name :tbxta
  
Synonyms : Q07998 / T-box transcription factor Ta / tbxta
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 14187540
Gene end: 14191592
  
Corresponding Affymetrix probe sets: Dr.1468.1.S1_at (Zebrafish Array)   NM_131162_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000141934
NCBI entrez gene - 30399     See in Manteia.
RefSeq - NM_131162
RefSeq Peptide - NP_571237
swissprot - Q07998
ZFIN ID - ZDB-GENE-980526-437
Ensembl - ENSDARG00000101576
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tbxtb / T-box transcription factor Tb / T* / TBXT* / P20293* / O15178* / T-box transcription factor T* / brachyury, T-box transcription factor T*ENSDARG0000003980661
tbx19 / T-box 19 / O60806* / Q99ME7* / T-box transcription factor TBX19 *ENSDARG0000007918752
tbx21 / T-box 21 / Q9JKD8* / Q9UL17* / T-box transcription factor TBX21 *ENSDARG0000000447330
tbr1b / T-box, brain, 1b / TBR1* / Q16650* / T-box, brain 1*ENSDARG0000000471228
mgaa / MGA, MAX dimerization protein a / MGA* / Q8IWI9* / A2AWL7* / MAX-associated protein * / MGA, MAX dimerization protein*ENSDARG0000007878427
eomesa / eomesodermin homolog a / EOMES* / O95936* / eomesodermin*ENSDARG0000000664027
tbr1a / T-box, brain, 1aENSDARG0000007625926
eomesb / eomesodermin homolog b / EOMES* / O95936* / eomesodermin*ENSDARG0000010424325
tbx6l / T-box 6, likeENSDARG0000000693921


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR002070  Transcription factor, Brachyury
 IPR008967  p53-like transcription factor, DNA-binding
 IPR018186  Transcription factor, T-box, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001707 mesoderm formation IGI
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0001889 liver development IGI
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0003140 determination of left/right asymmetry in lateral mesoderm IMP
 biological_processGO:0003143 embryonic heart tube morphogenesis IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0007498 mesoderm development IMP
 biological_processGO:0010159 specification of animal organ position IMP
 biological_processGO:0014028 notochord formation IMP
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030903 notochord development IMP
 biological_processGO:0031016 pancreas development IGI
 biological_processGO:0035462 determination of left/right asymmetry in diencephalon IMP
 biological_processGO:0035775 pronephric glomerulus morphogenesis IMP
 biological_processGO:0036342 post-anal tail morphogenesis IMP
 biological_processGO:0042663 regulation of endodermal cell fate specification IGI
 biological_processGO:0048565 digestive tract development IGI
 biological_processGO:0060028 convergent extension involved in axis elongation IGI
 biological_processGO:0060034 notochord cell differentiation IMP
 biological_processGO:0061053 somite development IMP
 biological_processGO:0061371 determination of heart left/right asymmetry IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 biological_processGO:0072045 convergent extension involved in nephron morphogenesis IMP
 biological_processGO:2000223 regulation of BMP signaling pathway involved in heart jogging IMP
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle aplastic , abnormal
Kupffers vesicle unlumenized , abnormal
Show

 ZFA:0000003 adaxial cell adaxial cell immature , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta malformed , abnormal
Show

 ZFA:0000022 floor plate floor plate quality , abnormal
Show

 ZFA:0000106 extension extension decreased length , abnormal
extension aplastic , abnormal
Show

 ZFA:0000108 fin fin decreased size , abnormal
Show

 ZFA:0000112 gut gut posterior region increased thickness , abnormal
Show

 ZFA:0000115 heart rudiment heart rudiment cardioblast anterior-lateral migration process quality , abnormal
Show

 ZFA:0000121 lateral plate mesoderm lateral plate mesoderm mislocalised , abnormal
lateral plate mesoderm bilateral symmetry , abnormal
Show

 ZFA:0000123 liver liver spatial pattern , abnormal
liver position , abnormal
Show

 ZFA:0000135 notochord notochord morphology , abnormal
notochord aplastic , abnormal
notochord absent , abnormal
notochord quality , abnormal
notochord malformed , abnormal
notochord structure , abnormal
notochord poorly differentiated , abnormal
notochord decreased size , abnormal
notochord undifferentiated , abnormal
notochord hypotrophic , abnormal
notochord decreased amount , abnormal
Show

 ZFA:0000140 pancreas pancreas spatial pattern , abnormal
pancreas position , abnormal
Show

 ZFA:0000149 primitive heart tube primitive heart tube bilateral symmetry , abnormal
Show

 ZFA:0000155 somite somite morphology , abnormal
somite decreased size , abnormal
somite decreased amount , abnormal
somite U-shaped , abnormal
somite quality , abnormal
somite fused with somite , abnormal
somite structure , abnormal
somite shape , abnormal
Show

 ZFA:0000213 habenula habenula determination of left/right symmetry disrupted , abnormal
habenula neurogenesis process quality , abnormal
Show

 ZFA:0000279 segmental plate segmental plate decreased amount , abnormal
Show

 ZFA:0000339 digestive system digestive system spatial pattern , abnormal
Show

 ZFA:0000360 heart tube heart tube mislocalised radially , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000509 epithalamus epithalamus determination of left/right symmetry disrupted , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum hypoplastic , abnormal
Show

 ZFA:0001058 caudal fin caudal fin truncated , abnormal
caudal fin morphology , abnormal
caudal fin kinked , abnormal
Show

 ZFA:0001089 myoseptum myoseptum quality , abnormal
Show

 ZFA:0001094 whole organism whole organism posterior region morphology , abnormal
whole organism shape , abnormal
whole organism lethal (sensu genetics) , abnormal
whole organism decreased length , abnormal
whole organism viability , abnormal
Show

 ZFA:0001115 trunk trunk morphology , abnormal
trunk wholly dorsalized , abnormal
trunk aplastic , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region malformed , abnormal
post-vent region absent , abnormal
post-vent region quality , abnormal
post-vent region shape , abnormal
post-vent region aplastic , abnormal
post-vent region mesenchymal cell degenerate , abnormal
post-vent region mesenchymal cell apoptotic , abnormal
post-vent region mesoderm decreased amount , abnormal
Show

 ZFA:0001257 medial floor plate medial floor plate increased width , abnormal
Show

 ZFA:0001670 notochord posterior region notochord posterior region absent , abnormal
Show

 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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